# Efficacy of Nebulized Long-Acting Bronchodilators (Formoterol and Revefenacin) vs. Short-Acting Bronchodilators (Albuterol and Ipratropium) in Patients Presenting to the Emergency Department With Acute Exacerbation of COPD (ECOPD)

> **NCT07721922** · PHASE4 · NOT_YET_RECRUITING · sponsor: **University of Tennessee Graduate School of Medicine** · enrollment: 280 (estimated)

## Conditions studied

- COPD Exacerbation

## Interventions

- **DRUG:** Revefenacin
- **DRUG:** formoterol fumarate
- **OTHER:** Placebo (Sterile Normal Saline)
- **DRUG:** Albuterol sulfate
- **DRUG:** Ipratropium Bromide

## Key facts

- **NCT ID:** NCT07721922
- **Lead sponsor:** University of Tennessee Graduate School of Medicine
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-09-01
- **Primary completion:** 2028-09-01
- **Final completion:** 2028-09-01
- **Target enrollment:** 280 (ESTIMATED)
- **Last updated:** 2026-08-17

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07721922

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07721922, "Efficacy of Nebulized Long-Acting Bronchodilators (Formoterol and Revefenacin) vs. Short-Acting Bronchodilators (Albuterol and Ipratropium) in Patients Presenting to the Emergency Department With Acute Exacerbation of COPD (ECOPD)". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07721922. Licensed CC0.

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