# Effect of Estradiol Pretreatment on Follicular Synchronization and IVF Outcomes in Women With Polycystic Ovary Syndrome Undergoing ICSI Using GnRH Antagonist Protocol

> **NCT07727863** · NA · COMPLETED · sponsor: **Cairo University** · enrollment: 61 (actual)

## Conditions studied

- PCOS GnRH Antagonist and GnRH Agonist IVF/ICSI Cycles
- IVF Outcomes

## Interventions

- **DRUG:** GnRH Antagonist Protocol
- **DRUG:** Estradiol Valerate 4mg

## Key facts

- **NCT ID:** NCT07727863
- **Lead sponsor:** Cairo University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2024-09-13
- **Primary completion:** 2026-02-17
- **Final completion:** 2026-06-21
- **Target enrollment:** 61 (ACTUAL)
- **Last updated:** 2026-07-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07727863

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07727863, "Effect of Estradiol Pretreatment on Follicular Synchronization and IVF Outcomes in Women With Polycystic Ovary Syndrome Undergoing ICSI Using GnRH Antagonist Protocol". Retrieved via MORVS 2026-10-21 from https://api.morvs.ai/clinical/NCT07727863. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*