# Efficacy and Safety of a Combined Topical Formula Versus Placebo in Patients With Melasma

> **NCT07727954** · NA · COMPLETED · sponsor: **University of Guadalajara** · enrollment: 40 (actual)

## Conditions studied

- Melasma

## Interventions

- **DRUG:** Topical azelaic acid 12% plus tranexamic acid 5%
- **DRUG:** Placebo topical formulation

## Key facts

- **NCT ID:** NCT07727954
- **Lead sponsor:** University of Guadalajara
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2026-06-12
- **Primary completion:** 2026-07-10
- **Final completion:** 2026-07-13
- **Target enrollment:** 40 (ACTUAL)
- **Last updated:** 2026-07-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07727954

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07727954, "Efficacy and Safety of a Combined Topical Formula Versus Placebo in Patients With Melasma". Retrieved via MORVS 2026-10-21 from https://api.morvs.ai/clinical/NCT07727954. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*