# Neoadjuvant Propranolol Plus SOX and Toripalimab for Locally Advanced Gastric/GEJ Adenocarcinoma

> **NCT07727993** · PHASE1,PHASE2 · NOT_YET_RECRUITING · sponsor: **Ting Liu** · enrollment: 49 (estimated)

## Conditions studied

- Gastric or Gastroesophageal Junction Adenocarcinoma
- Propranolol
- SOX Chemotherapy
- Toripalimab

## Interventions

- **DRUG:** propranolol
- **DRUG:** Toripalimab
- **DRUG:** Oxaliplatin
- **DRUG:** S-1

## Key facts

- **NCT ID:** NCT07727993
- **Lead sponsor:** Ting Liu
- **Sponsor class:** OTHER
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-08-01
- **Primary completion:** 2027-06-30
- **Final completion:** 2027-12-31
- **Target enrollment:** 49 (ESTIMATED)
- **Last updated:** 2026-07-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07727993

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07727993, "Neoadjuvant Propranolol Plus SOX and Toripalimab for Locally Advanced Gastric/GEJ Adenocarcinoma". Retrieved via MORVS 2026-10-21 from https://api.morvs.ai/clinical/NCT07727993. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*