# Impact Of A Phe-Restricted Diet On Gut Health In Children With PKU

> **NCT07728032** · — · RECRUITING · sponsor: **Birmingham Women's and Children's NHS Foundation Trust** · enrollment: 148 (estimated)

## Conditions studied

- Phenylketonuria

## Interventions

- **OTHER:** Phenylalanine-restricted diet alone
- **DRUG:** Sapropterin Dihydrochloride
- **DRUG:** Sepiapterin

## Key facts

- **NCT ID:** NCT07728032
- **Lead sponsor:** Birmingham Women's and Children's NHS Foundation Trust
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2025-10-01
- **Primary completion:** 2026-12
- **Final completion:** 2026-12
- **Target enrollment:** 148 (ESTIMATED)
- **Last updated:** 2026-10-06

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07728032

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07728032, "Impact Of A Phe-Restricted Diet On Gut Health In Children With PKU". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07728032. Licensed CC0.

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