# Evaluation of Hyaluronic Acid and Chlorhexidine Gel as an Adjunct to Minimally Invasive Non-surgical Therapy in the Treatment of Stage III and IV Periodontitis

> **NCT07731113** · NA · ACTIVE_NOT_RECRUITING · sponsor: **Cairo University** · enrollment: 72 (actual)

## Conditions studied

- Periodontology
- Periodontal Disease
- Periodontal Diseases
- Periodontitis (Stage 3)
- Gingivitis and Periodontal Diseases
- Stage III Periodontitis
- Stage IV Periodontitis
- Minimally Invasive Non-Surgical Therapy (MINST)
- Non-Surgical Periodontal Therapy
- Hyaluronic Acid
- Hyaluronic Acid and Chlorhexidine Gel
- Periofix Plus Gel
- Adjunctive Periodontal Therapy
- Clinical Attachment Level
- Probing Pocket Depth
- Biofilm Control

## Interventions

- **PROCEDURE:** MINST + CHX+HA gel
- **PROCEDURE:** MINST

## Key facts

- **NCT ID:** NCT07731113
- **Lead sponsor:** Cairo University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2026-03-01
- **Primary completion:** 2026-12-10
- **Final completion:** 2026-12-30
- **Target enrollment:** 72 (ACTUAL)
- **Last updated:** 2026-08-07


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07731113

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07731113, "Evaluation of Hyaluronic Acid and Chlorhexidine Gel as an Adjunct to Minimally Invasive Non-surgical Therapy in the Treatment of Stage III and IV Periodontitis". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07731113. Licensed CC0.

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