# Short-Term Changes in Salivary IL-6, TNF-α, and Periodontal Inflammation Following Sleeve Gastrectomy in Patients With Obesity: A Randomized Controlled Pilot Study

> **NCT07731412** · NA · COMPLETED · sponsor: **George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures** · enrollment: 32 (actual)

## Conditions studied

- Obesity
- Periodontitis

## Interventions

- **PROCEDURE:** Laparoscopic Sleeve Gastrectomy
- **OTHER:** Non-Surgical Obesity Management
- **BEHAVIORAL:** Standardized Oral-Hygiene Instructions

## Key facts

- **NCT ID:** NCT07731412
- **Lead sponsor:** George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2022-12-01
- **Primary completion:** 2025-04-15
- **Final completion:** 2025-12-30
- **Target enrollment:** 32 (ACTUAL)
- **Last updated:** 2026-07-28


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07731412

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07731412, "Short-Term Changes in Salivary IL-6, TNF-α, and Periodontal Inflammation Following Sleeve Gastrectomy in Patients With Obesity: A Randomized Controlled Pilot Study". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07731412. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*