# Hormone thERapy Effects on BRAin-HEART Health During the Menopausal Transition

> **NCT07732452** · PHASE4 · NOT_YET_RECRUITING · sponsor: **McGill University Health Centre/Research Institute of the McGill University Health Centre** · enrollment: 100 (estimated)

## Conditions studied

- Menopause
- Perimenopause
- Vasomotor Symptoms
- Cardiovascular Disease Risk Factor
- Menopausal Hormone Therapy
- Cardiac Remodeling
- Myocardial Fibrosis
- Microvascular Dysfunction
- Cognitive Function Assessment

## Interventions

- **DRUG:** Transdermal estradiol
- **DRUG:** Standard of care - non hormonal

## Key facts

- **NCT ID:** NCT07732452
- **Lead sponsor:** McGill University Health Centre/Research Institute of the McGill University Health Centre
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-11
- **Primary completion:** 2028-11
- **Final completion:** 2029-01
- **Target enrollment:** 100 (ESTIMATED)
- **Last updated:** 2026-07-29


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07732452

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07732452, "Hormone thERapy Effects on BRAin-HEART Health During the Menopausal Transition". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07732452. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*