# Cryotherapy, PGE2, NGF Levels and Pain After Endodontic Retreatment

> **NCT07733700** · NA · NOT_YET_RECRUITING · sponsor: **Alanya Alaaddin Keykubat University** · enrollment: 100 (estimated)

## Conditions studied

- Asymptomatic Apical Periodontitis
- Endodontic Retreatment
- Cryotherapy

## Interventions

- **PROCEDURE:** Intracanal cryotherapy
- **PROCEDURE:** Room-temperature saline irrigation

## Key facts

- **NCT ID:** NCT07733700
- **Lead sponsor:** Alanya Alaaddin Keykubat University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-08-01
- **Primary completion:** 2027-08-01
- **Final completion:** 2027-09-01
- **Target enrollment:** 100 (ESTIMATED)
- **Last updated:** 2026-07-29


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07733700

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07733700, "Cryotherapy, PGE2, NGF Levels and Pain After Endodontic Retreatment". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07733700. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*