# Pregnenolone Treatment for Alcohol Use Disorder and Major Depressive Disorder

> **NCT07734701** · PHASE2 · NOT_YET_RECRUITING · sponsor: **Sherwood Brown, MD, PhD** · enrollment: 100 (estimated)

## Conditions studied

- Alcohol Use Disorder (AUD)
- Major Depressive Disorder (MDD)

## Interventions

- **DRUG:** Pregnenolone
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT07734701
- **Lead sponsor:** Sherwood Brown, MD, PhD
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-10
- **Primary completion:** 2031-03
- **Final completion:** 2031-03
- **Target enrollment:** 100 (ESTIMATED)
- **Last updated:** 2026-08-24

## Collaborators

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- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07734701

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07734701, "Pregnenolone Treatment for Alcohol Use Disorder and Major Depressive Disorder". Retrieved via MORVS 2026-10-21 from https://api.morvs.ai/clinical/NCT07734701. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*