# The Effects of 5-methyltetrahydrofolate Supplementation in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease

> **NCT07740109** · NA · NOT_YET_RECRUITING · sponsor: **Tabriz University of Medical Sciences** · enrollment: 44 (estimated)

## Conditions studied

- Nonalcoholic Fatty Liver Disease
- Nonalcoholic Fatty Liver Disease (NAFLD)
- MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease
- MASLD
- NAFLD
- Metabolic Dysfunction-Associated Steatotic Liver Disease
- NAFLD (Nonalcoholic Fatty Liver Disease)
- NAFLD (Non-alcoholic Fatty Liver Disease)
- NAFLD - Non-Alcoholic Fatty Liver Disease
- NAFLD - Nonalcoholic Fatty Liver Disease

## Interventions

- **DIETARY_SUPPLEMENT:** 5-methyltetrahydrofolate (5-MTHF)
- **DIETARY_SUPPLEMENT:** placebo group

## Key facts

- **NCT ID:** NCT07740109
- **Lead sponsor:** Tabriz University of Medical Sciences
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-09-30
- **Primary completion:** 2027-08-30
- **Final completion:** 2027-08-30
- **Target enrollment:** 44 (ESTIMATED)
- **Last updated:** 2026-07-31


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07740109

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07740109, "The Effects of 5-methyltetrahydrofolate Supplementation in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07740109. Licensed CC0.

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