# A Study of Lumateperone Versus Placebo in Participants With Major Depressive Disorder

> **NCT07747389** · PHASE3 · NOT_YET_RECRUITING · sponsor: **Intra-Cellular Therapies, Inc.** · enrollment: 585 (estimated)

## Conditions studied

- Depressive Disorder, Major

## Interventions

- **DRUG:** Lumateperone
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT07747389
- **Lead sponsor:** Intra-Cellular Therapies, Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-10-20
- **Primary completion:** 2029-09-20
- **Final completion:** 2029-09-20
- **Target enrollment:** 585 (ESTIMATED)
- **Last updated:** 2026-08-31


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07747389

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07747389, "A Study of Lumateperone Versus Placebo in Participants With Major Depressive Disorder". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07747389. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*