# Tenecteplase or Reteplase as Bridging Thrombolysis Before Thrombectomy in Acute Ischemic Cerebrovascular Events

> **NCT07748039** · PHASE3 · NOT_YET_RECRUITING · sponsor: **Yongjun Wang** · enrollment: 1440 (estimated)

## Conditions studied

- Acute Ischemic Stroke
- Large Vessel Occlusion
- Anterior Circulation Brain Infarction

## Interventions

- **DRUG:** rhTNK-tPA (0.25mg/kg)
- **DRUG:** Reteplase 10 Units (U) plus a second dose of reteplase 10 U
- **PROCEDURE:** No thrombolysis (thrombectomy alone)

## Key facts

- **NCT ID:** NCT07748039
- **Lead sponsor:** Yongjun Wang
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-08-01
- **Primary completion:** 2029-03-01
- **Final completion:** 2029-08-01
- **Target enrollment:** 1440 (ESTIMATED)
- **Last updated:** 2026-08-05


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07748039

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07748039, "Tenecteplase or Reteplase as Bridging Thrombolysis Before Thrombectomy in Acute Ischemic Cerebrovascular Events". Retrieved via MORVS 2026-10-22 from https://api.morvs.ai/clinical/NCT07748039. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*