# A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of ONO-6414 Administered Orally in Healthy Adult Participants and Patients With Active Ulcerative Colitis

> **NCT07749768** · PHASE1 · RECRUITING · sponsor: **Ono Pharmaceutical Co., Ltd.** · enrollment: 90 (estimated)

## Conditions studied

- Ulcerative Colitis (UC)

## Interventions

- **DRUG:** ONO-6414
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT07749768
- **Lead sponsor:** Ono Pharmaceutical Co., Ltd.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-08-20
- **Primary completion:** 2027-12-31
- **Final completion:** 2028-01-31
- **Target enrollment:** 90 (ESTIMATED)
- **Last updated:** 2026-09-09


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07749768

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07749768, "A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of ONO-6414 Administered Orally in Healthy Adult Participants and Patients With Active Ulcerative Colitis". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07749768. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*