# Phase 1 Study in Healthy Adults to See How Sevabertinib Changes Metformin Levels in the Body

> **NCT07753252** · PHASE1 · NOT_YET_RECRUITING · sponsor: **Bayer** · enrollment: 40 (estimated)

## Conditions studied

- Healthy Participants

## Interventions

- **DRUG:** Metformin
- **DRUG:** Sevabertinib (BAY 2927088)

## Key facts

- **NCT ID:** NCT07753252
- **Lead sponsor:** Bayer
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-08-21
- **Primary completion:** 2026-09-21
- **Final completion:** 2026-09-28
- **Target enrollment:** 40 (ESTIMATED)
- **Last updated:** 2026-08-07


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07753252

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07753252, "Phase 1 Study in Healthy Adults to See How Sevabertinib Changes Metformin Levels in the Body". Retrieved via MORVS 2026-10-21 from https://api.morvs.ai/clinical/NCT07753252. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*