# Preliminary Clinical Feasibility Study of a Medical Device Enabling Brain Access Using Microbubble-Enhanced Sonication

> **NCT07754006** · PHASE1 · NOT_YET_RECRUITING · sponsor: **Gustave Roussy, Cancer Campus, Grand Paris** · enrollment: 6 (estimated)

## Conditions studied

- Recurrent Grade 4 Glioma
- Brain Metastases From Extra-cranial Solid Tumors

## Interventions

- **PROCEDURE:** Temporarily and locally induce permeability of the blood-brain barrier (sonication) using TheraOne

## Key facts

- **NCT ID:** NCT07754006
- **Lead sponsor:** Gustave Roussy, Cancer Campus, Grand Paris
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-09
- **Primary completion:** 2027-09
- **Final completion:** 2027-10
- **Target enrollment:** 6 (ESTIMATED)
- **Last updated:** 2026-08-10


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07754006

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07754006, "Preliminary Clinical Feasibility Study of a Medical Device Enabling Brain Access Using Microbubble-Enhanced Sonication". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07754006. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*