# Effectiveness of Epigallocatechin-3-Gallate (Green Tea Extract) as Adjunctive Locally Delivered Nanotherapeutic in the Treatment of Stage II Periodontitis

> **NCT07754253** · PHASE1 · RECRUITING · sponsor: **Mansoura University** · enrollment: 30 (estimated)

## Conditions studied

- Peridontitis

## Interventions

- **DRUG:** Ten patients with stage II periodontitis will receive epigallocatechin-3-gallate (EGCG)-loaded chitosan nanoparticulate gel injected into the periodontal pockets
- **DRUG:** chitosan nanoparticulate gel (CTN gel)
- **OTHER:** scaling and root planing (SRP) only.

## Key facts

- **NCT ID:** NCT07754253
- **Lead sponsor:** Mansoura University
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-03-16
- **Primary completion:** 2026-08-17
- **Final completion:** 2026-12-20
- **Target enrollment:** 30 (ESTIMATED)
- **Last updated:** 2026-08-10


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07754253

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07754253, "Effectiveness of Epigallocatechin-3-Gallate (Green Tea Extract) as Adjunctive Locally Delivered Nanotherapeutic in the Treatment of Stage II Periodontitis". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07754253. Licensed CC0.

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