# Off-Label Treatment With Immune Checkpoint Inhibitor Blockade

> **NCT07754292** · PHASE2 · NOT_YET_RECRUITING · sponsor: **Medical College of Wisconsin** · enrollment: 231 (estimated)

## Conditions studied

- Malignancy

## Interventions

- **DRUG:** One or more off-label ICIs alone or with other on-label ICI(s)
- **DRUG:** Off-label ICI(s) with targeted therapy
- **DRUG:** off-label ICI(s) with other agents that are not targeted (including, but not limited to, chemotherapy, hormonal therapy, immunotherapy other than ICIs) with or without targeted agents

## Key facts

- **NCT ID:** NCT07754292
- **Lead sponsor:** Medical College of Wisconsin
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-11-01
- **Primary completion:** 2032-11-01
- **Final completion:** 2036-11-01
- **Target enrollment:** 231 (ESTIMATED)
- **Last updated:** 2026-08-10


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07754292

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07754292, "Off-Label Treatment With Immune Checkpoint Inhibitor Blockade". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07754292. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*