# DOSE-UP: Dose Optimization for Smoking and E-Cigarette Use Pharmacotherapy

> **NCT07754578** · PHASE2 · NOT_YET_RECRUITING · sponsor: **Medical University of South Carolina** · enrollment: 321 (estimated)

## Conditions studied

- Dual Use of Cigarettes and E-cigarettes

## Interventions

- **BEHAVIORAL:** Text- and web-based support
- **DRUG:** Nicotine Replacement Therapy (NRT, nicotine patch)
- **DRUG:** Nicotine Replacement Therapy (NRT, nicotine patch)
- **DRUG:** Nicotine replacement therapy lozenge
- **DRUG:** Nicotine replacement therapy lozenge

## Key facts

- **NCT ID:** NCT07754578
- **Lead sponsor:** Medical University of South Carolina
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-10-10
- **Primary completion:** 2030-04-10
- **Final completion:** 2031-07-10
- **Target enrollment:** 321 (ESTIMATED)
- **Last updated:** 2026-08-11

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07754578

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07754578, "DOSE-UP: Dose Optimization for Smoking and E-Cigarette Use Pharmacotherapy". Retrieved via MORVS 2026-10-22 from https://api.morvs.ai/clinical/NCT07754578. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*