Abstract The population of people with HIV (PWH) older than 50 years now accounts for over 50% of PWH in the U.S. and is estimated to near 70% by 2030. As this population continues to age, they are faced with myriad health problems that impact quality of life (QoL). The National HIV/AIDS strategy 2022-2025 has acknowledged that we must focus interventions aimed at aging PLW beyond comorbidity and medication management to provide whole-person care that considers health-related social needs that impact up to 80% of health outcomes. In this project we will address the gap in the current understanding of QoL drivers and develop strategies for improving QoL for aging PWH that are centered in concept of whole-person care. The aims are to 1: conduct an environmental scan of the definition of QoL and barriers to improving QoL through a systematic reviews, surveys and qualitative methods; 2: develop strategies for intervening to improve QoL in adults aging with HIV through partner engagement around community-generated themes; 3: broadly disseminate recommended strategies to researchers, care providers, community organizations, community members and policy makers. This work has high potential to have an impact on clinical care, community programming and local policy through the connections of the study team to broad networks of clinicians (both geriatricians and HIV specialists), community organizations and various policy and advocacy boards, leading to care practice shifts, new conversations around QoL in community service organizations and discussions of legislation that could promote recommended strategies. Our broader dissemination strategy aims to reach nationally, to influence ideas about novel interventions and strategies to improve aging PWH lives, and we will continue to evaluate outcomes and disseminate successful strategies as they are implemented and demonstrate effectiveness at improving QoL for the aging PLW community.