# THE FC RECEPTOR OF THE HUMAN FETAL INTESTINE

> **NIH NIH K08** · MASSACHUSETTS GENERAL HOSPITAL · 1994 · $76,599

## Abstract

The scientific goal of this proposal is to elaborate on the specificity,
uniqueness, and functional significance of an Fc-receptor for IgG on the
human fetal intestinal surface, a potential entry site for antibodies and
antigens into the human fetus.  This receptor will be purified and
characterized and the gene coding for this receptor will be cloned and
related to other well-characterized Fc-R's responsible for immunity
transfer and/or antigen presentation.  The influence of known maturational
agents on the expression of this receptor will be examined to gain insight
into their potential role in modulating or preventing disease related to
immaturity of the transfer process, and more generally, to immaturity of
the gastrointestinal mucosal barrier.

## Key facts

- **NIH application ID:** 2194402
- **Project number:** 5K08HD000938-04
- **Recipient organization:** MASSACHUSETTS GENERAL HOSPITAL
- **SAM.gov UEI:** FLJ7DQKLL226
- **Principal Investigator:** ESTHER J ISRAEL
- **Activity code:** K08 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 1994
- **Award amount:** $76,599
- **Award type:** 5
- **Project period:** 1991-01-22 → 1995-12-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/2194402

## Citation

> US National Institutes of Health, RePORTER application 2194402, THE FC RECEPTOR OF THE HUMAN FETAL INTESTINE (5K08HD000938-04). Retrieved via MORVS 2026-10-25 from https://api.morvs.ai/grant/nih/2194402. Licensed CC0.

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