# REPRODUCTIVE BIOCHEMISTRY AND MEDICINE

> **NIH NIH P50** · COLUMBIA UNIVERSITY HEALTH SCIENCES · 1994 · $421,047

## Abstract

The Specialized Population Research Center proposed in this application
targets a synthesis of hypotheses and modern biomedical techniques in a
continuum of disciplines in reproductive sciences from molecular biology
to physiology. Close integration of principles, resources and expertise
is fundamental. The work includes ten projects which fall into the two
broad categories of neuroscience and early development; I, a study of
TGF-beta, II, an analyses of mammalian spermatogenesis; III, a study of
hap26 expression in Drosophila, IV, the study of the GnRH pulse
generator in primates, V, a study of the prenatal expression of growth
factor genes and receptors; VI, a study of GnRH networks in the rhesus
brain by neuroanatomical methods,; VII, analysis of placental CRH in
pregnant baboons, VIII, experiments with steroid/growth factors in
neurodevelopment; IX, study of sex steroid regulation of brain POMC and
LH and X, an analysis of proto-oncogene expression during mammalian
gametogenesis. Five biomedical cores are organized to expedite technical
usage of a primate colony, molecular cytology/histology techniques,
radioimmunoassay of steroids and proteins, cell and hybridization
culture, and a molecular biology facility.

## Key facts

- **NIH application ID:** 2194877
- **Project number:** 3P50HD005077-23S1
- **Recipient organization:** COLUMBIA UNIVERSITY HEALTH SCIENCES
- **SAM.gov UEI:** QHF5ZZ114M72
- **Principal Investigator:** GEORGIANA M JAGIELLO
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 1994
- **Award amount:** $421,047
- **Award type:** 3
- **Project period:** 1975-04-30 → 1996-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/2194877

## Citation

> US National Institutes of Health, RePORTER application 2194877, REPRODUCTIVE BIOCHEMISTRY AND MEDICINE (3P50HD005077-23S1). Retrieved via MORVS 2026-10-25 from https://api.morvs.ai/grant/nih/2194877. Licensed CC0.

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