# MATURATION OF COGNITIVE-RELATED BRAIN POTENTIALS

> **NIH NIH R01** · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · 1994 · $180,518

## Abstract

Event-related brain potentials (ERPs) will be recorded from children,
adolescents and adults using experimental designs that assess the effect of
encoding activity on pictures and words during on-line processing as well
as delayed memory tasks.  The main thrust of the proposal is to study
performance on explicit and implicit memory tasks in carefully controlled
designs, in which encoding task and stimulus form (i.e., pictures/words)
are manipulated so that all subjects are engaged in the same kind of
processing during encoding, and stimulus form can be varied within and
between study and test phases.  The proposal asks the general question how
do people of different ages differ (behaviorally and with respect to ERPs)
in the ways in which they process pictorial and verbal input on-line, and
the ways in which they remember and retrieve such input during delayed
memory tasks.  Behavioral evidence suggests an increase in encoding
efficiency as development unfolds, and that information processing of
pictorial and visually presented verbal material may undergo developmental
change.  There is some evidence of age-related differences in ERPs as a
function of stimulus form, and that ERP activity predictive of subsequent
memory performance changes as a function of age.  This ERP activity may
reflect elaboration, a memory strategy whose use is known to increase with
age.  Thus, ERP activity elicited by items during study that is predictive
of subsequent recognition is expected to differ among age groups as a
function of such developmental differences in memory function.  It is also
expected that N400 amplitude will reflect the magnitude of priming during
on-line and delayed memory tasks, and may change systematically across the
age range studied with the congruence between stimulus modality (pictures
or words) at study and test.  ERPs will be recorded from several scalp
placements in order to determine whether scalp distributions and, by
implication, their intracranial generators, differ systematically with age.
The data will be relevant to the developmental course of semantic
processing and memory function, and their physiological underpinnings.

## Key facts

- **NIH application ID:** 2197153
- **Project number:** 5R01HD014959-10
- **Recipient organization:** NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC
- **SAM.gov UEI:** TYVNMW8FNQQ3
- **Principal Investigator:** DAVID FRIEDMAN
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 1994
- **Award amount:** $180,518
- **Award type:** 5
- **Project period:** 1981-06-01 → 1996-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/2197153

## Citation

> US National Institutes of Health, RePORTER application 2197153, MATURATION OF COGNITIVE-RELATED BRAIN POTENTIALS (5R01HD014959-10). Retrieved via MORVS 2026-10-25 from https://api.morvs.ai/grant/nih/2197153. Licensed CC0.

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