# STRUCTURE, ORGANIZATION, AND FUNCTION OF BINDIN

> **NIH NIH R01** · UNIVERSITY OF CALIFORNIA-IRVINE · 1994 · $154,699

## Abstract

DESCRIPTION (adapted from applicant's abstract): Dr. Glabe's objective
is to  elucidate the molecular basis for the species-specific interaction
of the  sperm and egg surfaces during fertilization in sea urchins.

Aim 1 is to determine the structure/function relationships of binding a
sperm  adhesive protein.

Aim 2 is to assess the structure/function relationships of an egg surface
receptor and how the receptor interacts with bindin.

Aim 3 is to determine the nature of the interaction of bindin with
phospholipid bilayers and the role of this interaction in fertilization.

## Key facts

- **NIH application ID:** 2198251
- **Project number:** 2R01HD021379-10
- **Recipient organization:** UNIVERSITY OF CALIFORNIA-IRVINE
- **SAM.gov UEI:** MJC5FCYQTPE6
- **Principal Investigator:** Charles G. Glabe
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 1994
- **Award amount:** $154,699
- **Award type:** 2
- **Project period:** 1983-01-01 → 1998-12-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/2198251

## Citation

> US National Institutes of Health, RePORTER application 2198251, STRUCTURE, ORGANIZATION, AND FUNCTION OF BINDIN (2R01HD021379-10). Retrieved via MORVS 2026-10-25 from https://api.morvs.ai/grant/nih/2198251. Licensed CC0.

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