# RACIAL/ETHNIC DIFFERENCES IN ADVERSE PREGNANCY OUTCOMES

> **NIH NIH R01** · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · 1991 · $99,470

## Abstract

The specific aims of this study are to 1) Compare 4 low
socioeconomic status groups -- blacks, whites, Mexican-
Americans in San Antonio and blacks in Detroit -- with respect to
a) several adverse pregnancy outcomes (including low birthweight)
and b) medical/obstetrical, environmental, demographic, social,
cultural, psychological, and behavioral characteristics that may
be associated with these outcomes.  2) Determine which factors
or configurations of factors are independently associated with
each outcome for the sample as a whole and for each group
considered separately, with special emphasis given to patterns of
interactions among independent variables.  The objective here is
to a) explain outcome differences among the three racial/ethnic
groups in San Antonio, focusing on why Mexican-Americans have
as favorable or more favorable outcomes than whites despite
having social characteristics that would appear to place them at
higher risk and much more favorable outcomes than blacks with
whom they share many risk factors and b) determine the effects
of relatively favorable (San Antonio) vs. unfavorable (Detroit)
regional environments on outcomes among blacks.  3) Suggest
culturally meaningfully interventions to modify risk factors.  In
order to achieve these aims, an explanatory model based on life
events, qualify of social support, and cultural, valuation of
pregnancy and childbearing will be tested.

The sample consists of 3000 black, white and Mexican-American
pregnant women (1000 per group) in San Antonio and 1000
pregnant blacks in Detroit utilizing health facilities for the
indigent.  Blacks (in San Antonio) and whites will be oversampled
using weighted, stratified sampling procedures.  Patients will be
recruited at their first prenatal visit.  Those who lack prenatal
care will be recruited after delivery.  Subjects will be interviewed
at 3 time points:  the first prenatal visit, 28-30 weeks gestation,
and after delivery.  Charts and birth/death certificates will be
used to determine neonatal mortality.  Data analysis will be based
upon univariate statistical analyses (analysis of variance and chi-
square or other nonparametric statistics) and multivariate
analyses (logistic regression, ordinary least-squares regression).
Maximum-likelihood methods for the analysis of covariance
structure, specifically the SIMPLIS or LISREL computer software,
will be used to estimate a measurement model of the dependent
variable.  New methods for the estimation of covariance structure
model with data violate the maximum-likelihood assumption will
be considered.

## Key facts

- **NIH application ID:** 2199064
- **Project number:** 5R01HD024149-04
- **Recipient organization:** UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
- **SAM.gov UEI:** C3KXNLTAAY98
- **Principal Investigator:** ROCHELLE N SHAIN
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 1991
- **Award amount:** $99,470
- **Award type:** 5
- **Project period:** 1988-09-01 → 1994-11-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/2199064

## Citation

> US National Institutes of Health, RePORTER application 2199064, RACIAL/ETHNIC DIFFERENCES IN ADVERSE PREGNANCY OUTCOMES (5R01HD024149-04). Retrieved via MORVS 2026-10-25 from https://api.morvs.ai/grant/nih/2199064. Licensed CC0.

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