# PREVENTION & CONTROL PHYSICAL FRAILTY IN MINORITY AGED

> **NIH NIH R01** · WAYNE STATE UNIVERSITY · 1992 · $198,436

## Abstract

Functional disability of the aged is largely associated with chronic
diseases that are highly prevalent among minorities.  Thus, a
multi-disciplinary team will conduct two linked prospective studies among
a Black elderly cohort that will, a) determine the incidence and
prevalence of hypertension and diabetes and their relationship with
functional disability among 1000 older Blacks, and, b) initiate a
medical-educational-psychosocial intervention among a 280 person subgroup
with hypertension co-existent with diabetes.  Part A, the epidemiological
study, will provide data about morbidity and mortality associated with
diabetes and hypertension, especially functional disability related to
these conditions and their complications.  This study will also provide
knowledge of the health risk behaviors (nutritional, smoking, alcohol and
exercise habits), health beliefs and attitudes, and patterns of health
service utilization of Black older persons with diabetes and/or
hypertension and determine their relationship with medical outcomes.
Little is known of the natural course of these conditions among Black
elderly and less is known of how diverse health and psychosocial factors
influence these outcomes.  Part B, the intervention study, will identify
Black aged persons that have hypertension coexistent with diabetes, but
no indications of physical frailty.  This study will be an intensive
medical, educational, and psychosocial program designed to reduce
progressive impairment.  It will focus on altering multiple risk factors
that are associated with diabetes and hypertension-related morbidity.
Specifically we will seem to prevent or reduce the prevalence of disease
complications, functional decline and death.  Since the multiple
consequences of diabetes and hypertension are highly prevalent among
older Blacks, a program with integrated secondary and tertiary prevention
strategies can help to diminish the likelihood of functional decline
among this population.  Both studies will be longitudinal with four (the
epidemiological study) and eight (the intervention study) assessment
points, respectively.  Data will be analyzed to determine correlates and
predictors of outcomes and, in the epidemiological study, these outcomes
will include cardiovascular, renal, ophthalmologic, and neurological
endpoints, as well as basic functional ability.

## Key facts

- **NIH application ID:** 3122332
- **Project number:** 1R01AG010428-01
- **Recipient organization:** WAYNE STATE UNIVERSITY
- **SAM.gov UEI:** M6K6NTJ2MNE5
- **Principal Investigator:** JOHN WALLER
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 1992
- **Award amount:** $198,436
- **Award type:** 1
- **Project period:** 1992-09-01 → 1994-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/3122332

## Citation

> US National Institutes of Health, RePORTER application 3122332, PREVENTION & CONTROL PHYSICAL FRAILTY IN MINORITY AGED (1R01AG010428-01). Retrieved via MORVS 2026-10-25 from https://api.morvs.ai/grant/nih/3122332. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*