# OSTEOPOROSIS AND FALLS IN MEXICAN-AMERICAN ELDERS

> **NIH NIH R01** · STANFORD UNIVERSITY · 1993 · $232,438

## Abstract

Little is known of the epidemiology of osteoporosis, falls and fractures in
Hispanic-Americans.  The proposed study would recruit 150 Mexican-American
women in the age range 65-84 years from San Mateo and Santa Clara Counties
in northern California, and would focus on the epidemiology of bone mineral
density and of falls.  Particular emphasis is given to the role of physical
frailty and environmental, cultural, and nutritional factors in the
causation and progression of low bone mineral density and falls.  A
baseline cross-sectional study would include the following measures: bone
mineral density in the hip, spine, distal radius, proximal radius, and
whole body calcium; frequency of falls in the past year (by questionnaire);
biochemical markers of bone turnover; skin pigmentation; tests of muscle
strength, gait, mobility, and balance; and (by questionnaire) information
on a variety of other putative risk factors for low bone mineral density
and for falls.  Study subjects would have the same measurements repeated
annually for four years.  The baseline cross-sectional survey would provide
data not currently available on the distribution of bone mineral density,
fall frequency, and other indicators of physical frailty in Mexican--
American women in this age group, and on factors correlated with bone
mineral density and on characteristics of women who fall.  The longitudinal
component would allow identification of predictors of bone mineral density
and fall frequency, as well as predictors of change over time in bone
mineral density; markers of bone turnover, and fall frequency.  Thus, this
study should provide new information on the frequency of low bone mineral
density and of falls, and of the roles of physical frailty and other
factors in the etiology Mexican-American women.

## Key facts

- **NIH application ID:** 3122359
- **Project number:** 5R01AG010454-03
- **Recipient organization:** STANFORD UNIVERSITY
- **SAM.gov UEI:** HJD6G4D6TJY5
- **Principal Investigator:** Jennifer Kelsey
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 1993
- **Award amount:** $232,438
- **Award type:** 5
- **Project period:** 1991-09-30 → 1996-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/3122359

## Citation

> US National Institutes of Health, RePORTER application 3122359, OSTEOPOROSIS AND FALLS IN MEXICAN-AMERICAN ELDERS (5R01AG010454-03). Retrieved via MORVS 2026-10-25 from https://api.morvs.ai/grant/nih/3122359. Licensed CC0.

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