# ASSESSMENT AND INTERVENTION--ADL IN ALZHEIMER'S DISEASE

> **NIH NIH R01** · CLEVELAND STATE UNIVERSITY · 1992 · $95,640

## Abstract

AD leads to decrements in ability to accomplish ADL and to increase in
behavioral reactions such as frustration and anger.  Existing instruments
which measure these problems are too gross to measure the small increments
of change which are the probable outcome of most interventions.  As a
result, few nonpharmacological interventions are well documented.

Specific aims of the project are to:

1)  Continue development of the Assessment Scale for Cognitively Impaired
Elderly (ASCI) to evaluate activities of daily living (ADL) and problem
behaviors of individuals with Alzheimer's disease (AD) to enable sensitive
and accurate measurement of performance.

2)  Examine relationships between neuropsychological deficits in procedural
memory and function.

3)  Examine relationships between disturbance in function and presence of
behavioral symptoms.

4)  Pilot test interventions which address procedural memory through
environmental, caregiver, and direct interventions to examine their
effectiveness in maximizing functional independence and minimizing
behavioral problems in individuals with AD.

The ASCI will be administered to 6 subjects at various levels of dementia.
Ratings of 20 raters will be analyzed using Rasch and other methods to
establish a true scale, and reliability and validity of the instrument.

Twenty-eight subjects will be involved in a counterbalanced, time series
study, 4 as controls, 24 receiving direct, caregiver, and environmental
interventions emphasizing procedural memory.  Evaluation will occur at 11
points, to determine which intervention(s), singly or in combination appear
to have a positive impact on ADL and behavioral problems.

## Key facts

- **NIH application ID:** 3122573
- **Project number:** 5R01AG010646-02
- **Recipient organization:** CLEVELAND STATE UNIVERSITY
- **SAM.gov UEI:** YKGMTXA2NVL6
- **Principal Investigator:** BETTE R BONDER
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 1992
- **Award amount:** $95,640
- **Award type:** 5
- **Project period:** 1991-09-30 → 1993-12-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/3122573

## Citation

> US National Institutes of Health, RePORTER application 3122573, ASSESSMENT AND INTERVENTION--ADL IN ALZHEIMER'S DISEASE (5R01AG010646-02). Retrieved via MORVS 2026-10-25 from https://api.morvs.ai/grant/nih/3122573. Licensed CC0.

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