# DYSPHAGIA IN ALZHEIMER'S DISEASE

> **NIH NIH R01** · DUKE UNIVERSITY · 1992 · $90,532

## Abstract

Non-cognitive symptoms of Alzheimer's disease (AD) include feeding
abnormalities, and aspiration pneumonia.  Though dysphagia is generally
recognized to be a major contributor to morbidity in Alzheimer's dementia,
information about this disorder is lacking.  Therefore, the objective of
this investigation is to examine the frequency and progression of dysphagia
in patients with AD.  Dysphagia severity (defined in this study as
oropharyngeal aspiration or risk for aspiration), will be described using a
videofluoroscopic modified barium swallow technique.  The swallowing
examination will occur at the patient's entry into the study, and 12 months
later.  Dysphagia severity will be correlated with cognitive status, eating
dependency, physical examination, head CT or head MRI abnormalities, and
the occurrence or re-occurrence of aspiration pneumonia.

## Key facts

- **NIH application ID:** 3122578
- **Project number:** 5R01AG010648-02
- **Recipient organization:** DUKE UNIVERSITY
- **SAM.gov UEI:** TP7EK8DZV6N5
- **Principal Investigator:** Jennifer Horner
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 1992
- **Award amount:** $90,532
- **Award type:** 5
- **Project period:** 1991-09-30 → 1994-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/3122578

## Citation

> US National Institutes of Health, RePORTER application 3122578, DYSPHAGIA IN ALZHEIMER'S DISEASE (5R01AG010648-02). Retrieved via MORVS 2026-10-25 from https://api.morvs.ai/grant/nih/3122578. Licensed CC0.

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