# MICROBIAL IRON METABOLISM

> **NIH NIH R01** · UNIVERSITY OF CALIFORNIA BERKELEY · 1991 · $130,059

## Abstract

The long-term objective of this research is to provide information on the
mode of iron absorption in microbial species, with emphasis on the
molecular mechanism of regulation.  Insufficient iron leads to anemia in
animal subject and to impaired crop yields in plants.  Excess iron promotes
infection and results in generation of tissue damaging oxygen radicals.  A
combination of biochemical and molecular biological methods will be used
for the study of iron absorption in two enteric bacterial species,
Escherichia coli and Salmonella typhimurium, and in the single-celled
basidiomycetous fungus, Rhodotorula pilimanae.

## Key facts

- **NIH application ID:** 3124179
- **Project number:** 5R01AI004156-30
- **Recipient organization:** UNIVERSITY OF CALIFORNIA BERKELEY
- **SAM.gov UEI:** GS3YEVSS12N6
- **Principal Investigator:** JOHN B NEILANDS
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 1991
- **Award amount:** $130,059
- **Award type:** 5
- **Project period:** 1976-05-01 → 1994-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/3124179

## Citation

> US National Institutes of Health, RePORTER application 3124179, MICROBIAL IRON METABOLISM (5R01AI004156-30). Retrieved via MORVS 2026-10-25 from https://api.morvs.ai/grant/nih/3124179. Licensed CC0.

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