# ANALYSIS OF MOLLUSCAN FAUNAS AND ASTAN SCHISTOSOMIASIS

> **NIH NIH R01** · THE ACADEMY OF NATURAL SCIENCES OF PHILADELPHIA · 1992 · $132,925

## Abstract

It is a relatively new finding that there is a vast radiation of Triculini
snails (Pomatiopsidae: Triculinae) throughout southern China actually or
potentially transmitting Schistosoma and Paragonimus.  The objectives here
are to continue pursuing systematic, phylogenetic and biogeographic
studies of Chinese Triculinae and to use the snail phylogenies to assess
the patterns of co-evolution of Schistosoma and Paragonimus with these
snails.  The studies will involve detailed comparative anatomy, molecular
genetic (allozyme population genetics and LrRNA sequencing), and
biogeography.  The work links to previous work done on the phylogeny of
Triculinae in S.E. Asia and India.  The systematics work in China is in
its infancy as detailed comparative anatomical data are now available for
only 17% of the Chinese Triculinae estimated to be >140 species, >12
genera.  With each excursion into the provinces, new genera, and species
involved in transmitting these two parasite genera are found.

Work in cooperation with the Institute of Parasitic Diseases in Shanghai
and Hangchow, with the Academia Sinica, Beijing and with Hubei Medical
College.  Collaborative work in Hangchow is synchronized with their
ongoing work on Paragonimus.  We will initiate allozyme molecular genetic
work on Triculinae in Hangchow.  Collaborative work in Shanghai is
synchronized our ongoing work on the molecular genetics of Oncomelania
(Pomatiopsidae: Pomatiopsinae) throughout China relative to regional
genetic differentiation of Schistosoma japonicum.

## Key facts

- **NIH application ID:** 3124942
- **Project number:** 5R01AI011373-18
- **Recipient organization:** THE ACADEMY OF NATURAL SCIENCES OF PHILADELPHIA
- **SAM.gov UEI:** NFLBGA5A1RB9
- **Principal Investigator:** GEORGE M DAVIS
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 1992
- **Award amount:** $132,925
- **Award type:** 5
- **Project period:** 1990-05-01 → 1993-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/3124942

## Citation

> US National Institutes of Health, RePORTER application 3124942, ANALYSIS OF MOLLUSCAN FAUNAS AND ASTAN SCHISTOSOMIASIS (5R01AI011373-18). Retrieved via MORVS 2026-10-25 from https://api.morvs.ai/grant/nih/3124942. Licensed CC0.

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