# PRINCIPLES OF SENSORY RECEPTION AND MOTOR FUNCTION

> **NIH NIH R01** · YALE UNIVERSITY · 1988 · $187,621

## Abstract

The overall goal of the proposed research is an understanding of the
operation of a specific system of sensory reception and behavior, namely
bacterial chemotaxis.  The system, although rudimentary by comparison with
behavior in higher organisms, is nonetheless quite complex.  Study of the
system contributes to an understanding of general principles of receptor
function and organization, integration of sensory information, biological
switching, and energy transduction.  It also provides a foundation of basic
knowledge regarding bacterial motility and behavior that can be of use in
applied areas, such as medical microbiology, agricultural microbiology, and
mechanisms of biodegradation.

Within the overall goal, effort in the next few years will be focussed
specifically on the composition, structure, and function of the effector
organelle--the bacterial flagellar motor--including its switching
elements.  The primary organisms under study will be Salmonella typhimurium
and Escherichia coli.

## Key facts

- **NIH application ID:** 3125131
- **Project number:** 5R01AI012202-15
- **Recipient organization:** YALE UNIVERSITY
- **SAM.gov UEI:** FL6GV84CKN57
- **Principal Investigator:** ROBERT M MACNAB
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 1988
- **Award amount:** $187,621
- **Award type:** 5
- **Project period:** 1977-01-01 → 1989-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/3125131

## Citation

> US National Institutes of Health, RePORTER application 3125131, PRINCIPLES OF SENSORY RECEPTION AND MOTOR FUNCTION (5R01AI012202-15). Retrieved via MORVS 2026-10-25 from https://api.morvs.ai/grant/nih/3125131. Licensed CC0.

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