# ASSEMBLY AND STRUCTURE OF BACTERIOPHAGE LAMBDA

> **NIH NIH R01** · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 1989 · $159,915

## Abstract

This research is directed toward understanding biological assembly
processes at the molecular level, using assembly of the bacteriophage
lambda virion as a model.  The research focuses on assembly processes in
which one protein influences or directs the assembly of another, and seeks
to understand the detailed mechanisms behind such events.  Specific
problems being addressed include the structure and regulation of the E.
coli GroE proteins, which are host proteins required for correct virus
assembly, the nature and role of protein processing during virus assembly,
and the mechanisms by which the tail tape measure protein determines tail
length.

## Key facts

- **NIH application ID:** 3125144
- **Project number:** 5R01AI012227-15
- **Recipient organization:** UNIVERSITY OF PITTSBURGH AT PITTSBURGH
- **SAM.gov UEI:** MKAGLD59JRL1
- **Principal Investigator:** ROGER W HENDRIX
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 1989
- **Award amount:** $159,915
- **Award type:** 5
- **Project period:** 1977-12-01 → 1990-11-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/3125144

## Citation

> US National Institutes of Health, RePORTER application 3125144, ASSEMBLY AND STRUCTURE OF BACTERIOPHAGE LAMBDA (5R01AI012227-15). Retrieved via MORVS 2026-10-25 from https://api.morvs.ai/grant/nih/3125144. Licensed CC0.

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