# PHYSIOLOGICAL STUDIES ON A PARASITIC NEMATODE

> **NIH NIH R01** · UNIVERSITY OF WISCONSIN-MADISON · 1988 · $155,610

## Abstract

The aim of the project is to understand the way the movement of a parasitic
nematode is controlled.  For the control of nematodes, which are important
human parasites, a detailed knowledge of their fundamental physiological
mechanisms will enable new drugs to be designed.  We propose to study the
motor nervous system of Ascaris in order to understand how the output
signals to muscles are generated and coordinated to produce locomotion.  We
will use anatomical, pharmacological and physiological techniques to
achieve this.  To increase the spectrum of drugs available to paralyze
nematodes we will also attempt to identify compounds that selectively
inhibit different classes of nerve cells in the system.

## Key facts

- **NIH application ID:** 3126168
- **Project number:** 5R01AI015429-10
- **Recipient organization:** UNIVERSITY OF WISCONSIN-MADISON
- **SAM.gov UEI:** LCLSJAGTNZQ7
- **Principal Investigator:** ANTONY O. STRETTON
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 1988
- **Award amount:** $155,610
- **Award type:** 5
- **Project period:** 1979-01-01 → 1989-12-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/3126168

## Citation

> US National Institutes of Health, RePORTER application 3126168, PHYSIOLOGICAL STUDIES ON A PARASITIC NEMATODE (5R01AI015429-10). Retrieved via MORVS 2026-10-25 from https://api.morvs.ai/grant/nih/3126168. Licensed CC0.

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