# PHYSIOLOGICAL STUDIES ON A PARASITIC NEMATODE

> **NIH NIH R01** · UNIVERSITY OF WISCONSIN-MADISON · 1993 · $195,671

## Abstract

The aim of the project is to understand the way the movement of a
parasitic nematode is controlled.  For the control of nematodes,
which are important human parasites, a detailed knowledge of
their fundamental physiological mechanisms will enable new drugs
to be designed.  We propose to study the motor nervous system of
Ascaris in order to understand how the output signals to muscles
are generated and coordinated to produce locomotion.  We will use
anatomical, pharmacological and physiological techniques to
achieve this.  To increase the spectrum of drugs available to
paralyzenematodes we will also attempt to identify compounds that
selectively inhibit different classes of nerve cells in the
system.

## Key facts

- **NIH application ID:** 3126172
- **Project number:** 5R01AI015429-15
- **Recipient organization:** UNIVERSITY OF WISCONSIN-MADISON
- **SAM.gov UEI:** LCLSJAGTNZQ7
- **Principal Investigator:** ANTONY O. STRETTON
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 1993
- **Award amount:** $195,671
- **Award type:** 5
- **Project period:** 1979-01-01 → 1994-12-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/3126172

## Citation

> US National Institutes of Health, RePORTER application 3126172, PHYSIOLOGICAL STUDIES ON A PARASITIC NEMATODE (5R01AI015429-15). Retrieved via MORVS 2026-10-25 from https://api.morvs.ai/grant/nih/3126172. Licensed CC0.

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