# GENETIC APPROACHES TO REGULATION OF LIPID METABOLISM

> **NIH NIH R01** · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · 1988 · $181,254

## Abstract

This project is concerned with the molecular mechanisms that regulate lipid
synthesis and degradation in bacterial.  The general approach is to isolate
mutants of Eschuechia coli defective in lipid synthesis or degradation.
These mutants are then studied by a combination of biochemical, genetic,
physiological, and biophysical methods.  Since regulation of lipid
metabolism bears directly on membrane composition and function, knowledge
of these mechanisms is needed for an understanding of the etiology of
defective cellular membranes observed in many diseases.

## Key facts

- **NIH application ID:** 3126318
- **Project number:** 5R01AI015650-11
- **Recipient organization:** UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN
- **SAM.gov UEI:** Y8CWNJRCNN91
- **Principal Investigator:** John E. Cronan
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 1988
- **Award amount:** $181,254
- **Award type:** 5
- **Project period:** 1979-01-01 → 1988-12-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/3126318

## Citation

> US National Institutes of Health, RePORTER application 3126318, GENETIC APPROACHES TO REGULATION OF LIPID METABOLISM (5R01AI015650-11). Retrieved via MORVS 2026-10-25 from https://api.morvs.ai/grant/nih/3126318. Licensed CC0.

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