STIMULATION OF EXTREMITY GROWTH BY ELECTRICAL FIELDS

NIH RePORTER · NIH · R01 · $232,449 · view on reporter.nih.gov ↗

Abstract

The long-term objective of this renewal proposal is to produce accelerated growth of the growth plate in Beagle puppies with capacitively coupled electricity. The specific aims are 1) to determine if an appropriate capacitively coupled electrical signal can produce significant, prolonged acceleration of the puppy radius as measured with three-dimensional biplanar roentgenography utilizing tantalum epiphyseal and diaphyseal markers, and 2) to determine the effect of the applied electrical field on growth plate closure, be it premature closure, delayed closure, or normal time of closure. Successful prolonged acceleration of the puppy radius will set the stage for the translation of this data to clinical application in the child with limb length inequality.

Key facts

NIH application ID
3154782
Project number
2R01AR013812-20A2
Recipient
UNIVERSITY OF PENNSYLVANIA
SAM.gov UEI
GM1XX56LEP58
Principal Investigator
Carl T. Brighton
Activity code
R01
Funding institute
NIH
Fiscal year
1991
Award amount
$232,449
Award type
2
Project period
1975-11-01 → 1994-01-31