# CLINICAL BIOMECHANICS OF THE CERVICAL SPINE

> **NIH NIH R01** · YALE UNIVERSITY · 1987 · $196,568

## Abstract

Cervical spine injuries, degenertion (spondylosis), nerve root compression
(radiculopathy) and spinal cord compression (myelopathy) are the major
causes of pain, deformity and neurological disfunction in the cervical
region.  Studies of the spinal column alone, while important, provide
limited information about the cord and nerve roots.  The purpose of the
present proposal is to study in a comprehensive manner the mechanical basis
of local, radicular and myelopathic symptomatology in the cervical spine.
Such information is not available presently.

This comprehensive study has three basic parts.  Firstly, to determine
ligamentous strains and intervertebral foramenal changes due to
physiological movements of the cervical spine.  Secondly, to measure
physiological movements of, and strains in,, the nerve roots and spinal
cord.  Finally, to quantify 3-dimensional anatomy of the cervical spine in
various physiological postures using cryomicrotome sectioning, X-rays and
CT-scans.

Significance of this work will be in several different areas.  The
comprehensive set of biomechanical data about the functioning relationships
between the various components of the cervical spine system, namely,
vertebrae, ligaments, spinal cord and nerve roots will be available for the
first time.  It will provide the basis for understanding the functioning of
the cervical spine system.  Thereby making it possible to correlate
precisely the anatomic derangements with clinical presentation of symptoms
in a patient.  It will also be helpful in the design of new and more
efficient diagonostic and treatment modalities for the various problems of
the cervical spine.

## Key facts

- **NIH application ID:** 3155779
- **Project number:** 5R01AR030361-06
- **Recipient organization:** YALE UNIVERSITY
- **SAM.gov UEI:** FL6GV84CKN57
- **Principal Investigator:** MANOHAR M PANJABI
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 1987
- **Award amount:** $196,568
- **Award type:** 5
- **Project period:** 1982-02-01 → 1988-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/3155779

## Citation

> US National Institutes of Health, RePORTER application 3155779, CLINICAL BIOMECHANICS OF THE CERVICAL SPINE (5R01AR030361-06). Retrieved via MORVS 2026-10-24 from https://api.morvs.ai/grant/nih/3155779. Licensed CC0.

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