# ETIOLOGY OF RHEUMATOID ARTHRITIS (RA) AND SLE

> **NIH NIH R01** · SUNY DOWNSTATE MEDICAL CENTER · 1987 · $157,064

## Abstract

The proposed research project focuses on studies designed to elucidate
basic causal mechanisms in systemic lupus erythematosus and related
disorders.  By the application of recently devised techniques based on
advances in nucleic acid chemistry and molecular biology, a detailed
analysis of circulating DNA in both normal individuals and SLE patients is
proposed.  This analysis is designed to elucidate basic causal mechanisms
including possible causal involvement of microorganisms in these diseases.
The use of recombinant DNA methodology will allow this work to be greatly
faciliated over that previously carried out in this laboratory.  Other
studies relevant to the role of extranuclear DNA and antibodies to it will
also be pursued as will studies designed to identify putative causative
microorganisms in these diseases.

## Key facts

- **NIH application ID:** 3156552
- **Project number:** 5R01AR033278-06
- **Recipient organization:** SUNY DOWNSTATE MEDICAL CENTER
- **SAM.gov UEI:** NJ14V2NZYM68
- **Principal Investigator:** CHARLES R STEINMAN
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 1987
- **Award amount:** $157,064
- **Award type:** 5
- **Project period:** 1983-02-01 → 1989-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/3156552

## Citation

> US National Institutes of Health, RePORTER application 3156552, ETIOLOGY OF RHEUMATOID ARTHRITIS (RA) AND SLE (5R01AR033278-06). Retrieved via MORVS 2026-10-25 from https://api.morvs.ai/grant/nih/3156552. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*