# ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION

> **NIH NIH R01** · OHIO STATE UNIVERSITY · 1989 · $116,320

## Abstract

The injury of the anterior cruciate ligament (ACL) resulting in
severe damage to the ligament is a common occurrence.  The
importance of the ACL to the proper function of the knee,
including load transmission across the joint and joint kinematics,
requires its restoration in ACL deficient knees if normal knee
function is to be made possible once again.  Some ACL
reconstruction surgical procedures have attained wide
acceptance.  As a result of biomedical studies, as well as
information gained in clinical investigations, these procedures
have steadily improved.  As part of the reconstruction procedure,
the ACL or its substitute is pretensioned by a prescribed amount.
The amount of this tension as well as the position of knee at
which it is applied varies from procedure to procedure.  Although
tensioning of the ligament is deemed necessary to ensure the
ligament's or substitute's participation in the transmission of loads
across the knee, too much tension will result in premature failure
of the repair.  This important aspect of ACL reconstruction is
addressed in this project and it is proposed that this will be
studied by evaluating the effects of ACL and ACL substitute
pretension upon the kinematics and stability of the knee and the
forces transmitted through the ligament during knee function.

## Key facts

- **NIH application ID:** 3159052
- **Project number:** 5R01AR039014-02
- **Recipient organization:** OHIO STATE UNIVERSITY
- **SAM.gov UEI:** DLWBSLWAJWR1
- **Principal Investigator:** NECIP BERME
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 1989
- **Award amount:** $116,320
- **Award type:** 5
- **Project period:** 1988-08-01 → 1991-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/3159052

## Citation

> US National Institutes of Health, RePORTER application 3159052, ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION (5R01AR039014-02). Retrieved via MORVS 2026-10-24 from https://api.morvs.ai/grant/nih/3159052. Licensed CC0.

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