# CNS TUMORS AND OCCUPATIONAL EXPOSURES

> **NIH NIH R01** · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · 1987 · $103,278

## Abstract

The specific aim of the proposed research is to evaluate the joint
etiologic importance of occupational exposures, environmental exposures and
cigarette smoking among newly diagnosed cases of adult male leukemia
residing in six Texas Gulf Coast counties.  All new cases occurring between
January 1982 and December 1986 will be included in the study.  Cases are
identified through a hospital-based ascertainment system and are confirmed
for study eligibility through a histopathlogic review.

The design is a population-based case-comparison study in which exposure
information is obtained through interview.  Two comparison subjects are
drawn from drivers' license tapes provided to the investigators by the
State of Texas, and frequency matched to cases by age and race.

The study area contains one of the larget petrochemical complexes in the
world, and is well suited for the study of the influence of occupations in
these industries.

Analysis of the data will be by histologic types of leukemia whenever
numbers permit.  Interactions among the primary risk factors will be
examined by use of the logistic model.  Other potentially important factors
to be examined include familial aggregation of leukemia and other cancer,
prior exposure to therapeutic radiation and chemotherapy, contact with sick
pets, and history of viral disease.

## Key facts

- **NIH application ID:** 3170487
- **Project number:** 5R01CA032584-05
- **Recipient organization:** UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
- **SAM.gov UEI:** ZUFBNVZ587D4
- **Principal Investigator:** Patricia A Buffler
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 1987
- **Award amount:** $103,278
- **Award type:** 5
- **Project period:** 1982-09-30 → 1988-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/3170487

## Citation

> US National Institutes of Health, RePORTER application 3170487, CNS TUMORS AND OCCUPATIONAL EXPOSURES (5R01CA032584-05). Retrieved via MORVS 2026-10-25 from https://api.morvs.ai/grant/nih/3170487. Licensed CC0.

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