# PSYCHOSOCIAL STRESS AND CANCER RISK: PROSPECTIVE STUDY

> **NIH NIH R01** · MOUNT SINAI SCHOOL OF MEDICINE OF CUNY · 1989 · $158,526

## Abstract

This is a continuation of a prospective study to investigate the
association between psychosocial stress and cancer mortality.  The aims of
this study are:  1) to determine the role of psychosocial stress variables
in predicting both total cancer and lung cancer mortality; and 2) to assess
the joint effects of psychosocial stress and immunological status on both
total cancer and lung cancer mortality.

Baseline psychosocial stress questionnaires have been administered to a
cohort of 1,669 asbestos insulation workers at high risk of developing
cancer.  Information has also been collected on immunological status,
health status, and important known risk factors for cancer including age,
smoking history and duration from onset of exposure to asbestos.

A comprehensive battery of questionnaires to assess psychosocial stress
will continue to be administered annually and mortality information will
continue to be collected.  It has been calculated that 225 cancer deaths,
including 130 lung cancer deaths will occur in this cohort by July, 1990.
The contribution of psychosocial stress in predicting cancer mortality will
be determined using multivariate statistical techniques, including Cox
proportional hazards regression.

Access to a high risk population, combined with a comprehensive battery of
psychosocial stress questionnaires in the context of a prospective study
will allow a more detailed and comprehensive understanding of the complex
relationship between psychosocial stress and cancer mortality than
presently exists.

## Key facts

- **NIH application ID:** 3172357
- **Project number:** 5R01CA034618-07
- **Recipient organization:** MOUNT SINAI SCHOOL OF MEDICINE OF CUNY
- **Principal Investigator:** LINDA A GLICKMAN
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 1989
- **Award amount:** $158,526
- **Award type:** 5
- **Project period:** 1983-06-01 → 1991-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/3172357

## Citation

> US National Institutes of Health, RePORTER application 3172357, PSYCHOSOCIAL STRESS AND CANCER RISK: PROSPECTIVE STUDY (5R01CA034618-07). Retrieved via MORVS 2026-10-25 from https://api.morvs.ai/grant/nih/3172357. Licensed CC0.

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