# STRUCTURE OF CARCINOGEN-NUCLEIC ACID COMPLEXES

> **NIH NIH R01** · UNIVERSITY OF ROCHESTER · 1988 · $125,698

## Abstract

The complexes of carcinogens with native DNA and synthetic
deoxyoligonucleotides will be studied.  The experiments are
designed to locate the most reactive sequences for the
carcinogens on plasmid DNA and fragments of oncogenes.  The
conformation of the complexes will be determined by using
circular dichroism and one- and two-dimensional NMR
spectroscopies.

## Key facts

- **NIH application ID:** 3172860
- **Project number:** 5R01CA035251-05
- **Recipient organization:** UNIVERSITY OF ROCHESTER
- **SAM.gov UEI:** F27KDXZMF9Y8
- **Principal Investigator:** THOMAS R KRUGH
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 1988
- **Award amount:** $125,698
- **Award type:** 5
- **Project period:** 1983-08-01 → 1990-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/3172860

## Citation

> US National Institutes of Health, RePORTER application 3172860, STRUCTURE OF CARCINOGEN-NUCLEIC ACID COMPLEXES (5R01CA035251-05). Retrieved via MORVS 2026-10-25 from https://api.morvs.ai/grant/nih/3172860. Licensed CC0.

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