# NONPARAMETRIC ANALYSIS OF CENSORED DATA

> **NIH NIH R01** · UNIVERSITY OF WISCONSIN-MADISON · 1988 · $35,505

## Abstract

The specific aims will include:

1. Analysis of Censored Data.

The paradigm of multiple imputation-estimation will be used to address:  a)
the estimation of the hazard function in the presence of right and/or left
censoring, truncation and interval censoring; b) the analysis of time to
onset of disease detectable only at death in survival/sacrifice
experiments; c) an approach for treating ties due to grouping in the Cox
model; and d) the regression analysis of lifetime data under a variety of
censoring schemes when one does not assume any particular parametric family
of survival distributions.

2. A. Calculation of the Posterior Distribution (Missing Data).

Tanner and Wong introduced the IE algorithm for the calculation of the
posterior distribution in the presence of missing data.  This specific aim
will be devoted to improve the efficiency of the IE algorithm and to apply
the algorithm to various statistical problems which will arise in
collaboration with investigators at the WCCC.  One important application is
the analysis of designed experiments with missing data.

B. Calculation of the Posterior Distribution (No Missing Data).

Tanner and Wong introduced a rejection algorithm for the calculation of
posterior distributions in the multinomial case.  This specific aim will be
devoted to extend the applicability of the algorithm, to improve the
efficiency of the algorithm and to apply the algorithm to various
statistical problems in cancer research.

3. Modeling Agreement/Disagreement Among Raters.

Tanner and Young introduced an approach for modeling agreement/disagreement
among raters.  In the proposed research, model-based measures of agreement
will be developed and investigated.

## Key facts

- **NIH application ID:** 3173021
- **Project number:** 5R01CA035464-05
- **Recipient organization:** UNIVERSITY OF WISCONSIN-MADISON
- **SAM.gov UEI:** LCLSJAGTNZQ7
- **Principal Investigator:** MARTIN A TANNER
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 1988
- **Award amount:** $35,505
- **Award type:** 5
- **Project period:** 1984-08-01 → 1989-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/3173021

## Citation

> US National Institutes of Health, RePORTER application 3173021, NONPARAMETRIC ANALYSIS OF CENSORED DATA (5R01CA035464-05). Retrieved via MORVS 2026-10-25 from https://api.morvs.ai/grant/nih/3173021. Licensed CC0.

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