# CASE-CONTROL STUDY OF MULTIPLE MYELOMA

> **NIH NIH R01** · UNIVERSITY OF SOUTHERN CALIFORNIA · 1987 · $139,342

## Abstract

This proposal is for a case-control study of multiple myeloma in Los
Angeles County.  The case-group will include 440 cases, 340 whites and 100
blacks, of multiple myeloma identified by the Los Angeles County/USC Cancer
Surveillance Program and interviewed by telephone over a five-year period.
Controls will be neighborhood controls from the residence of the case at
diagnosis who are matched to the case on date of birth (+5 years), sex, and
race.

The major hypothesis to be tested is that the etiology of multiple myeloma
is related to chronic antigenic stimulation especially in conjunction with
underlying immune abnormality, either genetically or environmentally
determined.  The following major subject areas are addressed by the
questionnaire:  occupational exposures, radiation exposure, hormonal
status, medical history, family medical history.  We plan to compare risk
factors in men and women and in blacks and whites and by class of
immunoglobulin (IgG or IgA) secreted by the malignant cells.

## Key facts

- **NIH application ID:** 3173959
- **Project number:** 5R01CA036388-03
- **Recipient organization:** UNIVERSITY OF SOUTHERN CALIFORNIA
- **SAM.gov UEI:** G88KLJR3KYT5
- **Principal Investigator:** RONALD K ROSS
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 1987
- **Award amount:** $139,342
- **Award type:** 5
- **Project period:** 1985-05-01 → 1990-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/3173959

## Citation

> US National Institutes of Health, RePORTER application 3173959, CASE-CONTROL STUDY OF MULTIPLE MYELOMA (5R01CA036388-03). Retrieved via MORVS 2026-10-25 from https://api.morvs.ai/grant/nih/3173959. Licensed CC0.

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