# SELECTIVE EXPOSURE RADIOGRAPHY

> **NIH NIH R01** · UNIVERSITY OF WISCONSIN-MADISON · 1987 · $113,796

## Abstract

During our presently funded two year feasibility study, a prototype
dot-matrix printing system using cerium oxide ribbons was used to fabricate
patient-specific radiographic compensation filters.  Phantom results
suggest that these filters result in improved visualization of structures
in areas which normally are poorly penetrated.

There is a proposal for a three-year program with the following specific
aims:

1. Development of a clinically practical selective exposure chest
radiography technique based on our compensation filters;

2. Clinical comparison of compensated and conventional chest radiography;

3. Theoretical and experimental feasibility studies of multi-energy
compensated chest radiography techniques.

The first specific aim includes several hardware and software developments
required for adequate printing speed and physical corrections to the test
shot data.  In addition, phantom optimization studies will be performed.

The clinical evaluation will be in two parts:  (1) quantitative comparison
of observer performance for detection of nodules in patients referred for
chest CT and (2) subjective evaluation of anatomical features in
compensated and uncompensated chest radiographs.

The multi-energy feasibility study will involve computer simulations and
phantom experiments designed to investigate potential techniques which
might combine the advantages of spatially selective exposure the
tissue-specific imaging.

## Key facts

- **NIH application ID:** 3174236
- **Project number:** 5R01CA036623-05
- **Recipient organization:** UNIVERSITY OF WISCONSIN-MADISON
- **SAM.gov UEI:** LCLSJAGTNZQ7
- **Principal Investigator:** Charles A. Mistretta
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 1987
- **Award amount:** $113,796
- **Award type:** 5
- **Project period:** 1983-08-01 → 1988-11-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/3174236

## Citation

> US National Institutes of Health, RePORTER application 3174236, SELECTIVE EXPOSURE RADIOGRAPHY (5R01CA036623-05). Retrieved via MORVS 2026-10-25 from https://api.morvs.ai/grant/nih/3174236. Licensed CC0.

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