# COMPUTERIZED THERMAL DOSIMETRY FOR HYPERTHERMIA

> **NIH NIH R01** · DARTMOUTH COLLEGE · 1989 · $212,343

## Abstract

Recently there has been renewed interest in the use of
hyperthermia (elevated temperatures in the range of 43-55
degrees C) as a treatment for cancer, particularly as an adjuvant
to radiation therapy and chemotherapy.  Two of the major
problems in hyperthermia are the design of epuipment to heat
deep-seated tumors and thermal dosimetry, i.e., adequate
knowledge of the temperature distributions produced by the
equipment.  The major objective of this research is to develop
computer-based software packages for calculating temperature
distributions for hyperthermia applicators.  Our long term
objectives are:  (1) to be able to evaluate and compare
theoretically existing hyperthermia systems for their capability to
deposit energy into the tumor volume and to produce desirable
temperature distributions, (2) to propose and evaluate new types
of systems that might come closer to meeting the desired
specifications for a clinical system, and (3) to develop algorithms
that can be used for patient treatment planning for hyperthemia.
The specific aims include:  (1) the development of numerical
methods for calculating the three-dimensional power deposition
patterns and temperature distributions for commonly used
hyperthermia systems; (2) studies of the optimum system
parameters for heating tumors at various sites within the body; (3)
comparative studies of three-dimensional models of various
hyperthermia systems; (4) the development of methods for
automated entry of specific patient anatomical information from
CT or other imaging modalities into the computer; and (5) the
development of two-dimensional software packages compatible
with existing workstations that can be easily transferred to other
institutions.

## Key facts

- **NIH application ID:** 3175076
- **Project number:** 5R01CA037245-06
- **Recipient organization:** DARTMOUTH COLLEGE
- **SAM.gov UEI:** EB8ASJBCFER9
- **Principal Investigator:** JOHN W STROHBEHN
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 1989
- **Award amount:** $212,343
- **Award type:** 5
- **Project period:** 1984-05-01 → 1992-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/3175076

## Citation

> US National Institutes of Health, RePORTER application 3175076, COMPUTERIZED THERMAL DOSIMETRY FOR HYPERTHERMIA (5R01CA037245-06). Retrieved via MORVS 2026-10-25 from https://api.morvs.ai/grant/nih/3175076. Licensed CC0.

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