# OBJECTIVE GRADING OF PROSTATE CARCINOMA

> **NIH NIH R01** · UNIVERSITY OF CHICAGO · 1991 · $227,123

## Abstract

DNA ploidy patterns in cell nuclei from cytologic and histologic samples
will be used to provide tumor diagnostic and prognostic information.  Our
rapid, computer-controlled, video-based microphotometer system allows the
recording of DNA-ploidy patterns within minutes, with statistically valid
sample sizes, thus making this valuable method practical as a routine
clinical laboratory test.  It is intended to standardize the methodology
for this purpose, to assemble and examine a clinical database to correlate
ploidy patterns with clinical implications, to establish objective measures
for ploidy pattern evaluation, and to establish the sensitivity for the
detection of aneuploidy.  An inexpensive, microprocessor-based microscope
attachment and graphic display has been designed as a prototype for a
practical pathology laboratory instrument.  (3)

## Key facts

- **NIH application ID:** 3175194
- **Project number:** 5R01CA037352-08
- **Recipient organization:** UNIVERSITY OF CHICAGO
- **SAM.gov UEI:** ZUE9HKT2CLC9
- **Principal Investigator:** MARLUCE BIBBO
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 1991
- **Award amount:** $227,123
- **Award type:** 5
- **Project period:** 1989-04-14 → 1994-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/3175194

## Citation

> US National Institutes of Health, RePORTER application 3175194, OBJECTIVE GRADING OF PROSTATE CARCINOMA (5R01CA037352-08). Retrieved via MORVS 2026-10-25 from https://api.morvs.ai/grant/nih/3175194. Licensed CC0.

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