# STRUCTURE-FUNCTION OF INTERFERON-GAMMA AND ITS RECEPTORS

> **NIH NIH R01** · NEW YORK UNIVERSITY · 1987 · $148,877

## Abstract

Various aspects of the actions of human interferon (IFN)-gamma will be
examined with the aid of biological and biochemical techniques.  Both
highly purified natural and recombinant, E. coli-derived IFN-gamma will be
employed in these studies.  Studies will include evaluations of the
relative efficiency of IFN-gamma in inhibiting various viral functions in
different cell systems and in some immunoregulatory activities.  We shall
also continue to explore regulatory interactions between IFN-gamma and some
other lymphokines and monokines.  Monoclonal antibodies specific for
IFN-gamma will be prepared and characterized with respect to their ability
to bind to and neutralize natural and recombinant IFN-gamma.  (HF)

## Key facts

- **NIH application ID:** 3175248
- **Project number:** 5R01CA037385-04
- **Recipient organization:** NEW YORK UNIVERSITY
- **SAM.gov UEI:** NX9PXMKW5KW8
- **Principal Investigator:** YUM K YIP
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 1987
- **Award amount:** $148,877
- **Award type:** 5
- **Project period:** 1984-02-01 → 1988-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/3175248

## Citation

> US National Institutes of Health, RePORTER application 3175248, STRUCTURE-FUNCTION OF INTERFERON-GAMMA AND ITS RECEPTORS (5R01CA037385-04). Retrieved via MORVS 2026-10-25 from https://api.morvs.ai/grant/nih/3175248. Licensed CC0.

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