# INTERVENTIONS FOR SMOKING PREVENTION AND CESSATION

> **NIH NIH R01** · UNIV OF MASSACHUSETTS MED SCH WORCESTER · 1988 · $284,606

## Abstract

This is a proposal for a randomized clinical trial of five different
physician antismoking interventions, all of which are designed to fit
readily into the context of outpatient medical practice.  Participants will
be 2000 new adult patients being seen for the first time by their study
physician.  The study physicians will be residents in clinical training in
the Departments of General Medicine and Family and Community Medicine who
are seeing patients in four medical and family practice clinics associated
with the Medical School.  It is estimated that 75 residents will
participate over the course of the study.  A multifaceted training program
has been developed which will fit conveniently into the regular residency
training procedures.  All residents will be trained to provide all five of
the different interventions, and specific protocols will be used to guide
residents in the appropriate treatment of individual patients according to
the condition to which that patient is randomly assigned.  The basic
experimental design is a 2 x 2 design with two different intensities of
physician intervention and two different intensities of therapeutic
followup; the fifth experimental condition results from adding nicotine
chewing gum to the maximal intervention/maximal folloup condition.  There
will be 400 patients in each of the five conditions.  All will be followed
for two years via phone contacts at months 3, 6, 12, 18 and 24
post-intervention.  All patients reporting smoking abstinence at 3, 12 or
24 months will be seen in person for collection of a salivary sample for
cotinine analysis for objective determination of smoking status.

Extensive psychosocial data will be collected to be used in assessing
patient characteristics and experiences associated with successful versus
unsuccessful smoking outcomes.

## Key facts

- **NIH application ID:** 3176475
- **Project number:** 5R01CA038360-05
- **Recipient organization:** UNIV OF MASSACHUSETTS MED SCH WORCESTER
- **SAM.gov UEI:** MQE2JHHJW9Q8
- **Principal Investigator:** JUDITH K OCKENE
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 1988
- **Award amount:** $284,606
- **Award type:** 5
- **Project period:** 1984-09-26 → 1989-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/3176475

## Citation

> US National Institutes of Health, RePORTER application 3176475, INTERVENTIONS FOR SMOKING PREVENTION AND CESSATION (5R01CA038360-05). Retrieved via MORVS 2026-10-25 from https://api.morvs.ai/grant/nih/3176475. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*